Research Article “Captisol®: an efficient carrier and solubilizing agent for essential oils and their components”

“Essential oils and their individual components have several biological properties and are used in cosmetics, food and pharmaceutical industries. However, their application still presents a challenge owing mainly to their volatility and their poor aqueous solubility and stability.
The aim of this study was to evaluate, for the first time, the ability of Captisol® (sulfobutylether-β-cyclodextrin, SBE-β-CD) and Captisol-G® (sulfobutylether-γ-cyclodextrin, SBE-γ-CD) to encapsulate the main volatile components of six essential oils (EOs), to enhance the aqueous solubility of these EOs and to generate controlled release systems. The performance of these CDs was compared to hydroxypropyl-β-cyclodextrin (HP-β-CD) and γ-cyclodextrin (γ-CD), respectively. Formation constants (Kf) of the 40 inclusion complexes were determined by Static Headspace-Gas Chromatography (SH-GC).(…)”
Kfoury M, Pipkin JD, Antle V, Fourmentin S. Captisol®: an efficient carrier and solubilizing agent for essential oils and their components. Flavour Fragr J. 2017;1–7. https://doi.org/10.1002/ffj.3395

Research article « Characterization of Portuguese Thymbra capitata, Thymus caespititius and Myrtus communis essential oils in topical formulations”

“As the personal care industry evolves, formulators are seeking innovative solutions for their formulations’ needs, and for ingredients that can offer multiple functions within formulations. Considering that essential oils (EOs) may present a wide spectrum of biological activities, the composition, antimicrobial and antioxidant activity of Portuguese Thymbra capitata, Thymus caespititius and Myrtus communis EOs were assessed in order to evaluate them as preservatives and antioxidants in topical emulsions.(…)”

Neves A, Marto J, Duarte A, et al. Characterization of Portuguese Thymbra capitata, Thymus caespititius and Myrtus communis essential oils in topical formulations. Flavour Fragr J. 2017;0:1–11. https://doi.org/10.1002/ffj.3393

Source : http://onlinelibrary.wiley.com/wol1/doi/10.1002/ffj.3393/full