5 New Patents- Technologies

1-Fragrance Deposition in Liquid Crystal Surfactant Systems

This invention from IFF relates to fragrance capsules dispersed in lyotropic liquid crystalline surfactant phases for improved deposition.


Fragrance capsules in liquid crystal surfactant phases

Reference: U.S. Patent Application 20150291910
Publication date: Oct. 15, 2015
Assignee: International Flavors & Fragrances Inc.

“According to this patent application, using encapsulated fragrances in personal care rinse-off compositions, i.e., body wash, conditioner, shampoo, etc., poses a challenge in that the capsules are difficult to deposit on skin and hair due to strong interactions with surfactants in the products. Previous work has shown that polymers can be added to the capsules and products to enhance deposition. However, the extent of deposition enhancement still is affected by the presence of surfactants.
As as result, the present invention relates to fragrance-containing capsule compositions dispersed in lyotropic liquid crystalline surfactant phases, as well as a consumer products containing them. The inventors have found that the performance of fragrance delivered in this manner is significantly enhanced, versus dispersing the capsules on their own.”

2-Semi-synthetic Fragrance Production

This highlight describes a semi-synthetic route to produce fragrance compounds.

2Semisynthetic routes to organic compounds

Reference: WIPO Patent Application WO/2015/157719
Publication date: Oct. 15, 2015
Assignee: Reg Life Sciences, LLC

“According to these inventors, currently, fragrance ingredients are produced via three routes: a) extraction from plants or animals, b) total chemical synthesis from petrochemicals, and c) fungal biotransformation of oleochemicals. Furthermore, a fragrance obtained from a plant or animal is considered a natural fragrance, and as such, is in high consumer demand and commands premium prices.
However, supply is limited as these compounds usually exist only in minute quantities in sometimes rare plants or wild animals. In addition, their characters strongly dependence on factors that are difficult to control, for example, the influence of weather and the risk of plant disease.
The present disclosure therefore relates to processes that combine the microbial production of organic intermediates with subsequent synthetic transformations. This provides compounds of industrial value.”

3-Aqueous-compatible Nanoparticle Skin Care

This pick relates to polydots to enable the formation of aqueous-compatible nanoparticle compositions for various skin treatments.

3Aqueous-compatible nanoparticle skin treatments

Reference: WIPO Patent Application WO/2015/157688
Publication date: Oct. 15, 2015
Assignee: Wake Forest University

“According to these inventors, conjugated polymers are readily soluble in organic solvents but insoluble in aqueous media. Such insolubility has limited their application by requiring aqueous solvents and/or phases.
In response, this invention relates to composite polymeric nanoparticle compositions that are compatible with aqueous-based media. The compositions consist of a photoluminescent and a photo-thermal component, and are used with a source of radiation that matches all or part of the absorption profiles of these components.
In some embodiments, this system can be used to treat diseased tissue, adipose tissue and/or tissue infected with microbial or viral agents, or altered or removed surgically. The treated tissue may also be ophthalmologic, such as retinal tissue, or dental tissue. Further, wound dressings are described employing said treatment system.”

4- Sonochemically Stabilized Coated Pigments

This highlight is a sonochemical approach to form meta-stable coated particles.

4Sonochemical activation for meta-stable substances

Reference: WIPO Patent Application WO/2015/157685
Publication date: Oct. 15, 2015
Assignee: The Research Foundation for the State University of New York

“This invention discloses a method for forming a particle having a core that is fully coated by a dual-layer coating comprising an inner hydrophilic composition, and an outer hydrophobic polymer.
The core particles are added to a hydrophilic solution and mixed together. The hydrophobic polymer is then added to form a mixture. The mixture is sonicated to coat the particles and the coated particles are separated and dried to form meta-stable coated particles.
Such surface treatment of pigments has been found, for example, to improve the ease with which they are incorporated into especially hydrophobic cosmetic formulations.”

5- ‘Mustard’ Skin Delivery

Today’s invention relates to plasma membrane vesicles extracted from plants of the mustard family (Brassicaceae cruciferae) for epidermal delivery applications.


Brassicaceae cruciferae (mustard family) transport proteins from for skin delivery

Reference: U.S. Patent 9138487
Publication date: Sept. 22, 2015
Assignee: Consejo Superior De Investigaciones Cientificas

“This disclosure refers to a procedure for obtaining plasma membrane vesicles derived from the Brassica plant, which are enriched in aquaporins and other membrane-transport proteins and could additionally contain other substances such as natural bioactive compounds, hygroscopic or chemical agents for pharmacological and therapeutic uses.
Specifically, the methodology for obtaining the plant-plasma membrane vesicles comprises: a) a first phase of stimulation (or elicitation), applying a combined process of both abiotic stress and a bioactive compound to the plant; and b) a second step of membrane vesicle extraction. In addition, the invention relates to a method for increasing these proteins of plant origin.”

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