ECHA- Ongoing consultations

Source: ECHA e-News, 26 August 2015‏
http://echa.europa.eu/view-article/-/journal_content/title/echa-e-news-26-august-2015

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Ongoing consultations
Testing
proposals

Start: 31 July 2015
Deadline: 14 September 2015

3 testing proposals

Start: 7 August 2015
Deadline: 22 September 2015

1 testing proposal

Identification of substances of very high concern

No ongoing consultations

Draft recommendation of substances for the Authorisation List

No ongoing consultations

Harmonised classification and labelling

Start: 14 July 2015
Deadline: 28 August 2015

1 CLH proposal

Start: 28 July 2015
Deadline: 11 September 2015

2 CLH proposals

Restrictions

Start: 18 March 2015
Deadline: 18 September 2015
1 restriction proposal

Start: 18 June 2015
Deadline: 18 December 2015
1 restriction proposal

Applications for authorisation

Start: 12 August 2015
Deadline: 7 October 2015
9 consultations

Calls for comments and evidence

No ongoing consultations

Biocides consultation

No ongoing consultations

Publicités

FutureTox III Conference- Society of Toxicology

The Society of Toxicology is planning the third in a series of Contemporary Concepts in Toxicology conferences on the theme “FutureTox: Pathways to Prediction.”

FutureTox III, to be held November 19-20 in Arlington, Virginia, will focus on building the high-throughput risk assessment paradigm to advance the science of in vitro data and in silico models.

The central question to be addressed by the conference is “What progress is being made to address challenges in implementing the emerging ‘big-data’ toolbox for regulatory decision-making?”

Abstracts are being accepted through September 15 for a poster session to be held the evening of November 19.

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Vision and Background:

The 21st Century vision and strategy for assessing toxicity (TT21C science or Tox21 hereafter) was developed with the intent to increase throughput, decrease cost, and optimize chemical data collection for increased utility and relevance to inform chemical safety decision-making. Central to this strategy is the ability to predict human health risks from emerging ‘‘big data” and novel in vitro data collections using in silico models for exposure and hazard assessment. Automated high-throughput screening (HTS) and high-content screening (HCS) of large chemical inventories, together with newer complex culture models utilizing human cells, microtissue systems, and integrative models, are now providing vast amounts of data that can be used to inform regulatory toxicity testing. These methods, together with novel approaches to model exposure and kinetics, creates an opportunity for a paradigm shift toward diversified and high-throughput risk assessment (HTRA) approaches for regulatory decision-making. Overall, the approach results in more rapid, more relevant, and more nimble discovery-screening and prioritization efforts with less reliance on animal testing. The time is right to discuss and debate how TT21C science, approaches, and technologies will be applied in risk assessment and regulatory decision-making.

“FutureTox” was a Society of Toxicology Contemporary Concepts in Toxicology (SOT CCT) conference held in 2012 that focused on challenges and opportunities associated with implementing 21st Century toxicity testing technologies and tools into improved, science-informed hazard prediction and risk assessment. It was followed in 2014 by “FutureTox II,” a CCT that focused on the science to advance an outcome paradigm where improvements to predictivity and concordance are based solely on in vitro/in silico approaches. FutureTox III is a CCT focusing on building the high throughput risk assessment paradigm, taking the science of in vitro data and in silico models forward; thus, the conference will explore the central question: What progress is being made to address challenges in implementing the emerging ‘big-data’’ toolbox for regulatory decision-making? The TT21C testing paradigm provides a sustainable solution for tomorrow’s challenges in “creating a safer and healthier world by advancing the science of toxicology” (SOT’s mission).


Source:

Information about the conference, including registration information, abstract submission instructions, and the conference program : http://www.toxicology.org/events/shm/cct/futureToxIII.asp

Cet article n’engage que son auteur/ This article is the sole responsibility of the author.

ICCVAM Advisory Committee to Meet

The Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) will meet on September 2 in the Rodbell Auditorium at NIEHS. SACATM is the advisory committee to ICCVAM.

Topics to be discussed at the September 2 meeting include updates on recent activities from NICEATM and ICCVAM member agencies; international interactions and current international issues surrounding chemical safety testing; approaches to measuring success in replacement, reduction, and refinement of animal use (“3Rs”) for safety testing; and creation of a U.S. 3Rs roadmap and strategy.

Interested persons may attend the meeting in person or view the meeting via webcast.

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Information:

Site: http://ntp.niehs.nih.gov/about/org/sacatm/meetings/index.html

Location: David P. Rall Building in the Rodbell Auditorium, NIEHS, Research Triangle Park, NC.

Attending members: http://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2015/september/roster20150902_508.pdf

Agenda: http://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2015/september/agenda20150902_508.pdf

Background materials: http://ntp.niehs.nih.gov/about/org/sacatm/meetings/docs/2015/september/index.html

Register to view the webcast : http://ntp.niehs.nih.gov/about/bscwebmeeting/index.cfm?fa=c.register&meeting_id=1081

FDA Seeking Public Input Prior to International Meeting ICCR

« The Food and Drug Administration (FDA) is announcing a public meeting entitled “International Cooperation on Cosmetics Regulation (ICCR)Preparation for ICCR-9 Meeting.

The purpose of the meeting is to invite public input on various topics pertaining to the regulation of cosmetics. We may use this input to help us prepare for the ICCR-9 meeting that will be held November 4-6, 2015, in Brussels, Belgium.

You may present proposals for future ICCR agenda items, data, information, or views, orally or in writing, on issues pending at the public meeting. Time allotted for oral presentations may be limited to 10 minutes or less for each presenter.

Purpose of the Multilateral Framework on the ICCR:
to pave the way for the removal of regulatory obstacles to international trade while maintaining global consumer protection.
ICCR:
voluntary international group of cosmetics regulatory authorities from the United States, Japan, the European Union, Canada, and Brazil.
These regulatory authority members will enter into constructive dialogue with their relevant cosmetics industry trade associations and public advocacy groups.  ICCR members : Health Canada; the European Commission Directorate-General for Internal Market, Industry, Entrepreneurship, and Subject Matter Experts; the Ministry of Health, Labor, and Welfare of Japan; the Brazilian Health Surveillance Agency; FDA.
All decisions made by consensus will be compatible with the laws, policies, rules, regulations, and directives of the respective administrations and governments. Members will implement and/or promote actions or documents within their own jurisdictions and seek convergence of regulatory policies and practices. Successful implementation will need input from stakeholders.


Information
Notice of meeting, Ref. 80 FR 41506, pp 41506 -41507
Docket No. FDA-2015-N-0001, N° 2015-17248

Sites:

https://www.federalregister.gov/articles/2015/07/15/2015-17248/preparation-for-international-cooperation-on-cosmetics-regulation

http://www.fda.gov/Cosmetics/InternationalActivities/ICCR/default.htm

Agenda:  available  at http://www.fda.gov/Cosmetics/InternationalActivities/ICCR/default.htm

Date and Time:  public meeting  held on September 10, 2015, 2-4 p.m.

Location:  Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD 20740.

Transcripts: will be accessible at http://www.regulations.gov.

 Cet article n’engage que son auteur/ This article is the sole responsibility of the author.

New OECD Test Guidelines Available

Organisation for Economic Co-operation and Development (OECD) adopted four new test guidelines:

  • Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene
  • Test No. 491: Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage
  • Test No. 492: Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage
  • Test No. 493: Performance-Based Test Guideline for Human Recombinant Estrogen Receptor (hrER) In Vitro Assays to Detect Chemicals with ER Binding Affinity

OECD also published updates of 11 previously adopted test guidelines for assessing a wide range of chemical hazards.

Most of the new or updated test guidelines describe methods with the potential to reduce or replace animal use for chemical testing.
OECD test guidelines represent internationally agreed-upon testing methods used by government, industry, and independent laboratories to characterize potential chemical hazards.

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Source:
Texts available at OECD Site
http://www.oecd-ilibrary.org/environment/oecd-guidelines-for-the-testing-of-chemicals-section-4-health-effects_20745788